Enhanced Cell-Surface Engineering of CAR-Macrophag

kaggle2026-01-22 更新2026-02-14 收录

CAR-巨噬细胞疗法

免疫治疗优化

数据链接：

https://www.kaggle.com/datasets/freederiaresearch/enhanced-cell-surface-engineering-of-car-macrophag 数据链接链接失效反馈

官方服务：

资源简介：

**Abstract:** This research details a novel approach to improving the efficiency

摘要：本研究详述了一种用于提升效率的新颖方法

创建时间：

2026-01-22

Massively parallel engineering of persistent CAR-Ts [CLASH]

CAR-T细胞工程

免疫治疗优化

To identify immune-related gene perturbations that enhance CAR-T cell persistence in in vitro and in vivo settings, we generated thousands of CAR-T variants using the CLASH platform and evaluated crRN

NIAID Data Ecosystem40

Tumor-associated macrophages-educated reparative macrophages promote diabetic wound healing

糖尿病伤口愈合

CAR-巨噬细胞疗法

Inspired by tumor-associated macrophages (TAMs) that produce abundant immunosuppressive and proliferative factors in tumor development, we generate macrophages to recapitulate TAMs reparative function

NIAID Data Ecosystem20

DataSheet_1_T-BET and EOMES Accelerate and Enhance Functional Differentiation of Human Natural Killer Cells.pdf

NK细胞功能障碍

免疫治疗优化

T-bet and Eomes are transcription factors that are known to be important in maturation and function of murine natural killer (NK) cells. Reduced T-BET and EOMES expression results in dysfunctional NK

NIAID Data Ecosystem20

Senescent cancer-associated fibroblasts in pancreatic adenocarcinoma impair CD8+ T cell activation and limit responsiveness to immunotherapy in mice

胰腺癌免疫微环境

免疫治疗优化

Senescent cells within tumors and their stroma exert complex pro- and anti-tumorigenic functions, yet the potential for targeting such senescent cells for improved therapy remains largely unknown. Her

NIAID Data Ecosystem20

Metabolic Reprogramming via targeting the ACOD1/KEAP1/NRF2 axis promotes polarization and anti-tumor activity of human CAR-iMACs in solid tumors. Metabolic Reprogramming via targeting the ACOD1/KEAP1/NRF2 axis promotes polarization and anti-tumor activity of human CAR-iMACs in solid tumors

CAR-巨噬细胞疗法

实体瘤免疫治疗

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

NIAID Data Ecosystem20