Summary of pharmacokinetic parameters of i.v. BG00010.

aPharmacokinetic parameters for BG00010 i.v. 0.3 μg/kg were not calculable due to low serum concentrations of BG00010. bOne subject in the BG00010 1 μg/kg cohort was excluded due to low serum concentrations of BG00010. cOne subject in the BG00010 3 μg/kg cohort was excluded due to a high serum concentration of BG00010 at predose and low subsequent serum concentrations. AUCinf, area under the serum concentration-time curve from time zero to infinity; Cl, total body clearance; Cmax, maximum observed serum concentration; i.v., intravenous; s.c., subcutaneous; SD, standard deviation; Tmax, time to Cmax; t½,terminal half-life; Vss, steady-state volume of distribution. Summary of pharmacokinetic parameters of i.v. BG00010.