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Synergistic, context-dependent and hierarchical functions of hematopoietic progenitor niche components.

ChEBI2012-08-24 更新2026-07-21 收录

干细胞生态位

细胞周期调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-33268 数据链接链接失效反馈

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Synergistic, context-dependent and hierarchical functions of hematopoietic progenitor niche components.

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创建时间：

2012-08-24

细胞周期调控

环境胁迫信号转导

The bacterial cell cycle has been extensively studied under standard growth conditions. How it is modulated in response to environmental changes remains poorly understood. Here, we demonstrate that th

NIAID Data Ecosystem60

PU.1 promotes cell cycle exit in the murine myeloid lineage associated with down-regulation of E2F1. Mus musculus

髓系细胞分化

细胞周期调控

A doxycycline-inducible system was used to induce PU.1 expression in cultured myeloid cell lines. The parent cell line used was BN (Kamath et al., Leukemia 22:1214-1225, 2008). Overall design: RNA was

NIAID Data Ecosystem40

Arrest of G(1)-S Progression by the p53-Inducible Gene PC3 Is Rb Dependent and Relies on the Inhibition of Cyclin D1 Transcription

细胞周期调控

肿瘤抑制基因

The p53-inducible gene PC3 (TIS21, BTG2) is endowed with antiproliferative activity. Here we report that expression of PC3 in cycling cells induced accumulation of hypophosphorylated, growth-inhibitor

PubMed Central30

Fluorescence fluctuation analysis reveals PpV dependent Cdc25 protein dynamics in living embryos

细胞周期调控

胚胎发育蛋白质动力学

The protein phosphatase Cdc25 is a key regulator of the cell cycle by activating Cdk-cyclin complexes. Cdc25 is regulated by its expression levels and post-translational mechanisms. In early Drosophil

NIAID Data Ecosystem50

CIL:39672

细胞周期调控

基因突变显微成像

10-hour timelapse of the double mutant Clb2dbΔ, Clb5Δ, which has the destruction box region of the CLB2 gene, on the cell cycle control system in budding yeast. The yeast, Saccharomyces cerevisia, ar

NIAID Data Ecosystem30

Synergistic, context-dependent and hierarchical functions of hematopoietic progenitor niche components.

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