Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with 4,4',4''-(thiophene-2,3,5-triyl)triphenol

Crystal Structure of the ER-alpha Ligand-binding Domain (Y537S) in Complex with 4,4',4''-(thiophene-2,3,5-triyl)triphenol Descriptor: 4,4',4''-(thiene-2,3,5-triyl)triphenol, Estrogen receptor, NUCLEAR RECEPTOR COACTIVATOR 2 Authors: Nwachukwu, J.C, Srinivasan, S, Bruno, N.E, Nowak, J, Kojetin, D.J, Elemento, O, Katzenellenbogen, J.A, Nettles, K.W. Deposit date: 2016-10-11 Release date: 2017-01-18 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.497 Å) Cite: Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies. Cell Chem Biol, 24, 2017

ER-α配体结合域（Y537S突变体与4,4',4''-(噻吩-2,3,5-三基)三苯酚复合物的晶体结构
描述项：4,4',4''-(噻吩-2,3,5-三基)三苯酚、雌激素受体（Estrogen receptor）、核受体辅激活因子2（Nuclear Receptor Coactivator 2）
作者：Nwachukwu J.C.、Srinivasan S、Bruno N.E.、Nowak J、Kojetin D.J.、Elemento O、Katzenellenbogen J.A.、Nettles K.W.
存档日期：2016-10-11
发布日期：2017-01-18
最后修改日期：2024-03-06
实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率2.497埃（Å）
引用文献：配体对ERα的系统结构生物学分析预测细胞对环境雌激素与抗激素治疗反应。刊载于《细胞化学与生物学》（Cell Chem Biol），第24卷，2017年