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Alterations in chromosome spatial compartmentalization classify prostate cancer progression [array]

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE172098
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Through a systematic analysis of chromosome conformation capture in a cohort of cells that model cancer progression, San Martin et.al. find that rearrangement of the 3D genome structure in prostate cancer is a potential mechanism for disease exacerbation and that genome-wide compartment identity can classify cancer according to progression Analysis of the gene expression of a cohort of cell lines in the continuum of prostate cancer, from adenocarcinoma to bone metastatic
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2022-06-21
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