Ercc3

ENCODES a protein that exhibits 3'-5' DNA helicase activity (ortholog); ATP hydrolysis activity (ortholog); promoter-specific chromatin binding (ortholog); INVOLVED IN embryonic organ development; response to hypoxia; apoptotic process (ortholog); PARTICIPATES IN altered nucleotide excision repair pathway; nucleotide excision repair pathway; RNA polymerase II transcription initiation pathway; ASSOCIATED WITH asphyxia neonatorum; Alzheimer's disease (ortholog); Arsenic Poisoning (ortholog); FOUND IN transcription factor TFIIH core complex; nucleoplasm (ortholog); transcription factor TFIID complex (ortholog); INTERACTS WITH (+)-pilocarpine; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene

编码一种表现3'-5' DNA解旋酶活性（同源物）；三磷酸腺苷水解活性（同源物）；启动子特异性染色质结合（同源物）；参与胚胎器官发育；对缺氧的响应；凋亡过程（同源物）；参与改变核酸切除修复途径；核酸切除修复途径；RNA聚合酶II转录起始途径；与新生儿窒息、阿尔茨海默病（同源物）、砷中毒（同源物）相关；存在于转录因子TFIIH核心复合体；核质（同源物）；转录因子TFIID复合体（同源物）；与(+)-毛果芸香碱、2,3,7,8-四氯二苯并-对-二恶英、2,6-二硝基甲苯相互作用。