CD157 marks tissue resident vasculoreparative endothelial stem cells
收藏NIAID Data Ecosystem2026-03-10 收录
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https://www.ncbi.nlm.nih.gov/sra/DRP004037
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资源简介：
To maintain tissue oxygen demands, new blood vessels are derived from existing vessels through angiogenesis. A role for adult stem cells in this process remains obscure. Here we identify CD157 (bst1, bone-marrow stromal antigen-1) as a marker of tissue resident vascular endothelial stem cells (VESC) in large arteries and veins in organs. Tissue resident CD157+ VESC display properties of endothelial colony-forming cells in vitro and transplantation of a single VESC in the liver generates donor-derived portal vein, sinusoids, and central vein endothelial cells. We monitored gene expression of the individual cells.
创建时间：
2018-02-10
