Human B lactate dehydrogenase complexed with NAD+ and 4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid

Human B lactate dehydrogenase complexed with NAD+ and 4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid Descriptor: 4-HYDROXY-1,2,5-OXADIAZOLE-3-CARBOXYLIC ACID, L-lactate dehydrogenase B chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Cameron, A, Read, J, Tranter, R, Winter, V.J, Sessions, R.B, Brady, R.L, Vivas, L, Easton, A, Kendrick, H, Croft, S.L, Barros, D, Lavandera, J.L, Martin, J.J, Risco, F, Garcia-Ochoa, S, Gamo, F.J, Sanz, L, Leon, L, Ruiz, J.R, Gabarro, R, Mallo, A, De Las Heras, F.G. Deposit date: 2004-04-21 Release date: 2004-05-11 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (3 Å) Cite: Identification and Activity of a Series of Azole-based Compounds with Lactate Dehydrogenase-directed Anti-malarial Activity. J.Biol.Chem., 279, 2004

与烟酰胺腺嘌呤二核苷酸（NAD+）及4-羟基-1,2,5-恶二唑-3-羧酸结合的人类B型乳酸脱氢酶。描述符：4-羟基-1,2,5-恶二唑-3-羧酸、L-乳酸脱氢酶B链、烟酰胺腺嘌呤二核苷酸（NAD+）。作者：Cameron, A、Read, J、Tranter, R、Winter, V.J、Sessions, R.B、Brady, R.L、Vivas, L、Easton, A、Kendrick, H、Croft, S.L、Barros, D、Lavandera, J.L、Martin, J.J、Risco, F、Garcia-Ochoa, S、Gamo, F.J、Sanz, L、Leon, L、Ruiz, J.R、Gabarro, R、Mallo, A、De Las Heras, F.G。提交日期：2004年4月21日；发布日期：2004年5月11日；最后修改日期：2023年8月23日。实验方法：X射线衍射（分辨率3埃）。引用文献：《一系列基于唑类的乳酸脱氢酶靶向抗疟活性化合物的鉴定与活性》，《生物化学杂志》（J.Biol.Chem.），第279卷，2004年。