The nucleosomal barrier to promoter escape by RNA Polymerase II is overcome by the chromatin remodeler Chd1 [HiSeq]. Mus musculus
收藏NIAID Data Ecosystem2026-03-08 收录
下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJNA229126
下载链接
链接失效反馈官方服务：
资源简介：
We use a metabolic labeling strategy for directly measuring nucleosome turnover to determine the role of chromatin remodeler Chd1 on chromatin dynamics in mouse embryonic fibroblasts expressing with wildtype-Chd1 and dominant negative K510R-Chd1. We find that expression of K5 10R-Chd1 decreases nucleosome turnover at the promoter and increases turnover within the gene body. Overall design: 10 Illumina sequencing samples and 4 Nimblegen array samples
创建时间：
2013-11-19
