Crystal structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(n-hexylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+
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Crystal structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(n-hexylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+ Descriptor: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, Farnesyl pyrophosphate synthase, MAGNESIUM ION, ... Authors: Aripirala, S, Amzel, L.M, Gabelli, S.B. Deposit date: 2012-03-06 Release date: 2013-01-16 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Design, synthesis, calorimetry, and crystallographic analysis of 2-alkylaminoethyl-1,1-bisphosphonates as inhibitors of Trypanosoma cruzi farnesyl diphosphate synthase. J.Med.Chem., 55, 2012
克氏锥虫（Trypanosoma cruzi）法尼基二磷酸合酶（farnesyl diphosphate synthase）与[2-(正己基氨基)乙烷-1,1-二基]双膦酸及镁离子（Mg²+）复合物的晶体结构。相关组分：3-甲基丁-3-烯基三氢二磷酸酯、法尼基焦磷酸合酶、镁离子…… 作者：Aripirala S、Amzel L.M.、Gabelli S.B. 提交日期：2012-03-06；发布日期：2013-01-16；最后修改日期：2023-09-13。实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率2.65埃）。引用文献：《2-烷基氨基乙基-1,1-双膦酸酯作为克氏锥虫法尼基二磷酸合酶抑制剂的设计、合成、量热分析与晶体学研究》，J.Med.Chem., 55, 2012
创建时间：
2012-03-06
