Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered Through X-Ray Fragment Screening
收藏Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/5jat
下载链接
链接失效反馈官方服务：
资源简介：
Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered Through X-Ray Fragment Screening Descriptor: 3-{2-[(2',6-dimethyl[1,1'-biphenyl]-3-yl)amino]-1,3-thiazol-4-yl}propan-1-ol, CHLORIDE ION, DIMETHYL SULFOXIDE, ... Authors: Day, P.J. Deposit date: 2016-04-12 Release date: 2016-05-25 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.04 Å) Cite: Exploitation of a Novel Binding Pocket in Human Lipoprotein-Associated Phospholipase A2 (Lp-PLA2) Discovered through X-ray Fragment Screening. J.Med.Chem., 59, 2016
本研究主题：通过X射线片段筛选发现人脂蛋白相关磷脂酶A2（Lp-PLA2）的新型结合口袋。数据集描述：包含3-{2-[(2',6-二甲基[1,1'-联苯]-3-基)氨基]-1,3-噻唑-4-基}丙-1-醇、氯离子、二甲基亚砜等。作者：Day, P.J. 存入日期：2016-04-12，发布日期：2016-05-25，最后修改日期：2024-05-08。实验方法：X射线衍射（分辨率2.04埃）。引用文献：《通过X射线片段筛选发现人脂蛋白相关磷脂酶A2（Lp-PLA2）的新型结合口袋》，《Journal of Medicinal Chemistry》，59卷，2016年
创建时间：
2016-04-12
