BCLXL PROTAC degrader DT2216 targets secondary plasma cell leukemia addicted to BCLXL for survival
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP415464
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资源简介:
We demonstrated that secondary Plasma Cell Leukemia, addicted to BCLXL, a small but a very challenging group of patients, could benefit from DT2216, underpinning its clinical evaluation. Overall design: RNA CD138 positive human plasma cells were extracted with RNeasy Mini Kit (Qiagen) and sequenced on 3'ends.
创建时间:
2024-05-01



