Discovery of novel potent triple IKZF1/2/3 degraders for the treatment of hematological cancers
收藏国家人口健康科学数据中心2026-06-06 收录
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Through subsequent investigations into structure-activity relationships (SAR) and protein degradation mechanisms, we developed a novel and highly effective candidate, MGD-22, demonstrates potent inhibition of hematological cancer growth across a broad range of models and overcame acquired resistance to IMiDs.
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北京蛋白质组研究中心创建时间：
2025-01-08
