Data underlying the publication: "Twisted clustered pinhole collimation for improved high-energy preclinical SPECT/PET"

This study focused on the development of a novel collimator design, named the <em>Twisted Clustered Pinhole</em> (TCP) collimator. This design represents an evolution of the <em>Clustered Pinhole</em> (CP) collimator and is characterized by a modified cluster geometry, in which the pinholes are twisted around the cluster’s central axis. This configuration allows the use of smaller pinhole opening angles, which is particularly advantageous for applications targeting high-energy gamma emissions as it further reduce the chances of pinhole edge penetration.The study was carried out through simulations, where the proposed design was introduced and evaluated in comparison to the previous collimator. Data generated using simulation software were used to assess the collimator’s performance and to reconstruct images of specifically designed phantoms. The collected data include simulation macros, collimator design scripts, performance analysis scripts, and reconstructed images. All datasets, scripts, and software used in the paper <em>“Twisted clustered pinhole collimation for improved high-energy preclinical SPECT/PET”</em> have been archived. A user manual detailing how to operate the software tools employed in this work is also included.

本研究聚焦于一种新型准直器（collimator）设计的开发，该设计被命名为扭曲簇状针孔（Twisted Clustered Pinhole，TCP）准直器。该设计是簇状针孔（Clustered Pinhole，CP）准直器的迭代升级方案，其特征在于改良的簇几何构型，针孔围绕簇的中心轴发生扭转。此种构型可采用更小的针孔张角，对于高能伽马射线发射相关应用尤为有利，因为它进一步降低了伽马射线穿透针孔边缘的概率。本研究通过仿真实验开展，将所提出的新型准直器与前代CP准直器进行对比评估。研究借助仿真软件生成的数据，对准直器的性能进行评估，并对定制设计的体模完成成像重建。所收集的数据集包含仿真宏命令、准直器设计脚本、性能分析脚本以及重建图像。本文《用于改进型高能临床前单光子发射计算机断层成像术（SPECT）/正电子发射断层显像术（PET）的扭曲簇状针孔准直技术》中所使用的全部数据集、脚本及相关软件均已归档。此外，本数据集还附带一份用户手册，详细说明了如何操作本研究中用到的各类软件工具。