The effects of transcriptional activator engineering on the transcriptome of Penicillium oxalicum

The filamentous fungus Penicillium oxalicum can secret various enzymes for efficient saccharification of plant biomass materials. Expression of the constitutively active forms of transcriptional activators ClrB, XlnR and AraR could trigger the production of different sets of lignocellulolytic enzymes. Here, the transcriptomes of the three engineered strains were compared with that of wild type in the medium without carbon source. A total of 12 samples were analyzed, which include biological triplicates. The wild-type strain 114-2 was used as a control.