shRNA knockdown of the transcription factor NFYA in H322 and HCT116

ChEBI2016-07-03 更新2026-07-12 收录

癌症基因功能

转录因子敲降

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-70543 数据链接链接失效反馈

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shRNA knockdown of the transcription factor NFYA in H322 and HCT116

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2016-07-03

Non-phosphorylatable cyclin D1 mutant potentiates endometrial hyperplasia and drives carcinoma with Pten loss

肿瘤发生机制

癌症基因功能

Cyclin D1 is a regulatory subunit of cyclin-Dependent Kinases 4 and 6 (CDK4/6) and regulates progression from G1 to S phase of the cell cycle. Dysregulated cyclin D1-CDK4/6 contributes to tumor develo

NIAID Data Ecosystem40

Supplementary Data Table S9 from Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells

癌症基因功能

RNAi功能验证

Supplementary Table S9 showing the impact of removal of mutant KRAS in human cancer cell lines in vitro by RNAi by mining the DepMap database

NIAID Data Ecosystem20

Uncovering the dosage-dependent roles of Arid1a in gastric tumorigenesis for combinatorial drug therapy [RNA-Seq]

癌症基因功能

组合疗法

Gastric cancer (GC) is one of the most common deadly cancers in the world. Although patient genomic data have identified ARID1A, a key chromatin remodeling complex subunit, as the second most frequent

NIAID Data Ecosystem20

Supplemental Table 3 from Jak1–STAT3 Signals Are Essential Effectors of the USP6/TRE17 Oncogene in Tumorigenesis

癌症基因功能

肿瘤发生机制

NF dataset p< 0.05

NIAID Data Ecosystem30

Gene expression profiles after knockdown of Nardilysin in TMK-1 gastric cancer cells

癌症基因功能

RNA干扰抗病毒机制

Nardilysin (NRDc), a metalloendopeptidase of the M16 family, has been reported to promote the ectodomain shedding and resulting activation of various growth factors and cytokines, but its role in canc

NIAID Data Ecosystem20

shRNA knockdown of the transcription factor NFYA in H322 and HCT116

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