Distinct expansions of Vγ9Vδ2 cells from 60 EOC patients in response to BrHPP and to Zol.

Vδ2+ T cell frequencies in expanded cells (Vδ2+CD3+ staining) and Vδ2+ T cell numbers generated from 1×106 PBMCs were measured 14 days after BrHPP or zoledronate (Zol) stimulation; data are presented as means +/− SEM or medians with [first quartile - third quartile]; The Vδ2+ T cell frequency of 70% and the Vδ2+ T cell number of 2×106 (corresponding to the mean of the first quartile values of expanded Vδ2+ T cell number with BrHPP and with Zol) were both used as cut-off values to distinguish efficient expansions (≥70% and ≥2×106 cells) from inefficient expansions (<70% or <2×106 cells); four PBMC groups were distinguished: R, Zol-LR, Br-LR and LR; Nb. (%) denotes the number of samples and the corresponding percentage; BrHPP and Zol data were compared using $paired t-test or #wilcoxon matched pairs test; p value <0.05 indicates a significant difference.