This is a translational clinical genomic study using next generation DNA sequencing from 77 patients with metastatic colorectal cancer (mCRC) for comprehensive analyses. Along with exome-derived param
In this experiment we sequenced a collection of genes identified as being mutated in a Sleeping Beauty Screen in a mouse colorectal Cancer Model in human tumours collected from patients with germline
Background: Hereditary factors are thought to play a role in at least one third of patients with colorectal cancer, but only a limited proportion of these have mutations in known high-penetrant genes.