The Mechanism of Gene Regulation in Recurrent Vulvovaginal Candidiasis (RVVC Group)

Kunming mice were infected with Candida albicans, and transcriptome sequencing and analysis were performed to investigate the mechanism by which gene X mediates recurrent vulvovaginal candidiasis (RVVC) through the Y signaling pathway, thereby providing novel insights and potential therapeutic targets for the treatment of RVVC. Overall design: Establish mouse models of vulvovaginal candidiasis (VVC) and recurrent vulvovaginal candidiasis (RVVC). Perform high-throughput transcriptome sequencing on vaginal epithelial tissues from the control, VVC, and RVVC groups, followed by screening for differentially expressed genes (DEGs).