IGF2BP3 mediates m6A-modified E2F2 stability to affect neuroblastoma progression [m6A-seq]
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https://www.ncbi.nlm.nih.gov/sra/SRP482621
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资源简介：
We report a previously unrecognized role of IGF2BP3 in survival of neuroblastoma cells. To explore IGF2BP3-dependent gene regulation and m6A modification, RNA-seq and m6A-seq analysis was conducted and the differently expressed/modified genes were revealed in the IGF2BP3-knockdown SK-N-BE(2) cells in comparison to control group. Overall design: RIP assay was performed using m6A antibody in SK-N-BE(2) cells transfected with control shRNA (sh-NC) or sh-IGF2BP3, and the enriched RNA was sequenced with input sample.
创建时间：
2024-12-31
