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Mechanistic and structural insight into the functional dichotomy between interleukin-2 and interleukin-15

ChEBI2012-11-01 更新2026-07-21 收录

细胞因子作用机制

免疫信号传导

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-40350 数据链接链接失效反馈

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Mechanistic and structural insight into the functional dichotomy between interleukin-2 and interleukin-15

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创建时间：

2012-11-01

免疫细胞响应

细胞因子作用机制

human primay macrophages (hMDMs) were unstimulated, stimulated with IFNg or costimulated with IFNg and TNFa for 18h Overall design: human primay macrophages (hMDMs) were unstimulated, stimulated wi

NIAID Data Ecosystem50

Table_1_Tas2R signaling enhances mouse neutrophil migration via a ROCK-dependent pathway.pdf

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中性粒细胞迁移

Type-2 bitter taste receptors (Tas2Rs) are a large family of G protein-coupled receptors that are expressed in the oral cavity and serve to detect substances with bitter tastes in foods and medicines.

NIAID Data Ecosystem40

Table_7_Transcriptional Profiling of Monocytes Deficient in Nuclear Orphan Receptors NR4A2 and NR4A3 Reveals Distinct Signalling Roles Related to Antigen Presentation and Viral Response.xlsx

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核受体功能研究

The nuclear receptor sub-family 4 group A (NR4A) family are early response genes that encode proteins that are activated in several tissues/cells in response to a variety of stressors. The NR4A family

NIAID Data Ecosystem20

IL-17A and IL-22 synergistically stimulated human epithelial cells inducing IL-8.

细胞因子作用机制

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(A) IL-8 production at 24 hours by AGS cells in response to IL-22 and IL-17A as measured by ELISA. p-value is based on ANOVA test with Dunnett’s correction for multiple comparisons ***p

Figshare2016-03-16 更新40

Interleukin-2 induces β(2)-integrin-dependent signal transduction involving the focal adhesion kinase-related protein B (fakB)

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整合素介导磷酸化

β(2) integrin molecules are involved in a multitude of cellular events, including adhesion, migration, and cellular activation. Here, we studied the influence of β(2) integrins on interleukin-2 (IL-2)

PubMed Central1998-06-09 更新20

Mechanistic and structural insight into the functional dichotomy between interleukin-2 and interleukin-15

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