MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB
收藏reactome.org2025-01-21 收录
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资源简介:
Phosphorylation of CEBPB (C/EBP-beta) transcription factor on threonine residue T235 happens downstream of activated RAS, is mediated by MAPKs - likely MAPK3 (ERK1) and MAPK1 (ERK2), and positively affects CEBPB-mediated transcription of IL6 (Nakajima et al. 1993).
CEBPB(C/EBP-β)转录因子在苏氨酸残基T235上的磷酸化过程发生在激活的RAS下游,由MAPKs介导,可能性较高的为MAPK3(ERK1)和MAPK1(ERK2),且该过程对CEBPB介导的IL6(Nakajima等,1993年)转录具有正向影响。
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