Crystal structure of mouse acetylcholinesterase inhibited by aged VX and sarin
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Crystal structure of mouse acetylcholinesterase inhibited by aged VX and sarin Descriptor: 1-ETHOXY-2-(2-ETHOXYETHOXY)ETHANE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYLCHOLINESTERASE, ... Authors: Hornberg, A, Tunemalm, A.-K, Ekstrom, F. Deposit date: 2007-02-13 Release date: 2007-04-17 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Crystal Structures of Acetylcholinesterase in Complex with Organophosphorus Compounds Suggest that the Acyl Pocket Modulates the Aging Reaction by Precluding the Formation of the Trigonal Bipyramidal Transition State. Biochemistry, 46, 2007
经老化维埃克斯(VX)与沙林(sarin)抑制的小鼠乙酰胆碱酯酶(acetylcholinesterase)晶体结构
描述符:1-乙氧基-2-(2-乙氧基乙氧基)乙烷、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、乙酰胆碱酯酶(acetylcholinesterase)……
作者:Hornberg, A、Tunemalm, A.-K、Ekstrom, F.
存档日期:2007-02-13
发布日期:2007-04-17
最后修改日期:2023-12-13
实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率2.6埃(Å)
引用文献:《与有机磷化合物结合的乙酰胆碱酯酶晶体结构表明酰基口袋通过阻止三角双锥过渡态形成调控老化反应》,《生物化学(Biochemistry)》,第46卷,2007年
创建时间:
2007-02-13



