Transcriptional profiling of naïve and in vitro activated B cells from WT and DOT1L KO mice
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https://www.ncbi.nlm.nih.gov/sra/SRP225794
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We studied the role of the histone methyltransferase DOT1L in B cell development and differentiation. Here we generated RNA-seq data naive B cells from (WT) MB1+/-;Dot1L+/+ and Dot1L KO (MB1+/-;Dot1Lfl/fl) mice. This data was to define tissue specific expression signatures and it was compared with H3K79me2 ChIP-seq data from the same subsets. Overall design: RNA-seq from MACS sorted CD19+ naïve and actiavted B cells WT and Dot1L KO mice
创建时间:
2021-02-09



