RNA-seq of LSC-like, non-LSC and Mature populations from human AML patient samples

ChEBI2023-03-01 更新2026-07-12 收录

白血病干细胞转录组

急性髓系白血病异质性

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-11976 数据链接链接失效反馈

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RNA-seq of LSC-like, non-LSC and Mature populations from human AML patient samples

创建时间：

2023-03-01

RNA-sequencing of WT and Asic3-null leukemia-initiating cells (LICs). Mus musculus

白血病干细胞转录组

离子通道基因功能

To tease apart the downstream signaling triggered by the Asic3-mediated ion current, RNA-sequencing analyses were conducted with WT and Asic3-null LICs. We found 199 genes were significantly up-regula

NIAID Data Ecosystem50

Genome-wide expression analysis of wide-type and PirBTM MLL-AF9 LSCs

白血病干细胞转录组

MLL-AF9基因融合分析

Genome-wide expression analysis of wide-type and PirBTM MLL-AF9 LSCs

ChEBI2012-03-08 更新30

Leukemic initiation in Jam-C-deficient HSPC reveals AP-1/TNF- gene expression signature as a biomarker for AML. Leukemic initiation in Jam-C-deficient HSPC reveals AP-1/TNF- gene expression signature as a biomarker for AML

急性髓系白血病生物标志物

白血病干细胞转录组

The leukemic stem cell score 17 (LSC-17) based on stemness gene expression signature is recognized as indicator of poor disease outcome in acute myeloid leukemia (AML). However, our understanding of t

NIAID Data Ecosystem30

Autonomous TGFÃ signaling induces phenotypic variation in human acute myeloid leukemia

急性髓系白血病异质性

TGF-β信号通路

Heterogeneity of leukemia stem cells (LSCs) is involved in their collective chemoresistance. To eradicate LSCs, it is necessary to understand the mechanisms underlying their heterogeneity. Here, we ai

NIAID Data Ecosystem40

Induction and Therapeutic Targeting of Human NPM1c+ Myeloid Leukemia in the Presence of Autologous Immune System in Mice

NPM1c+急性髓系白血病机制

白血病干细胞转录组

Purpose: To understand the molecular mechanisms underlying NPM1c-mediated tumorigenesis by comparing the transcriptome of de novo generated bulk human leukemic cells and leukemic stem cells Overall de

NIAID Data Ecosystem30

RNA-seq of LSC-like, non-LSC and Mature populations from human AML patient samples

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