RNA-Seq data of NCI-H82 cells expressing a Dox-On pRB (pTripZ RB1) grown in the presence or absence of DOX and then treated with vehicle or AZD2811.

We report changes in gene expression in response to reexpression of pRB in NCI-H82 cells and how AZD2811 differentially affects the transcriptome of these cells depending on whether or not pRB is expressed. Two biological replicates (10_18 and 10_21) for analysis of gene expression (RNA-Seq) in NCI-H82 cells that are grown in the presence (pRB+) or absense (pRB-) of DOX and treated with AZD2811 or not.