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eEF2K activity determines synergy to PI3K and MEK inhibitors in combination in cancer cells

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NIAID Data Ecosystem2026-03-13 收录
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To understand the mechanisms involved in synergy to PI3Ki + MEKi treatment, we performed a global phosphoproteomics analysis in 3 different cancer cell lines treated with a MEK inhibitor (Trametinib) and a PI3K inhibitor (Pictilisib) at 500 nM individually or in combination for one hour.

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2022-04-25
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