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The human Ewing's Sarcoma oncoprotein EWS-FLI1 causes developmental defects in zebrafish embryos

ChEBI2011-11-01 更新2026-07-21 收录

尤文肉瘤

斑马鱼发育毒性

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-31185 数据链接链接失效反馈

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The human Ewing's Sarcoma oncoprotein EWS-FLI1 causes developmental defects in zebrafish embryos

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创建时间：

2011-11-01

组蛋白甲基化分析

斑马鱼发育毒性

3-deazaneplanocin A (DZNeP) is a promising cancer drug affecting the methylation status of histone lysine residues. To investigate the specificity and mode of action of DZNeP, zebrafish embryos displa

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BMI-1 promotes Ewing sarcoma tumorigenicity independent of CDKN2a-repression. Homo sapiens

尤文肉瘤

BMI-1基因功能研究

Over-expression of the polycomb group gene BMI-1 is implicated in the pathogenesis of many human cancers. In this study, we investigate the role of BMI-1 as a functional oncogene in the Ewing’s Sarcom

NIAID Data Ecosystem50

Additional file 4 of CRISPR-Cas9 knockout screening identifies KIAA1429 as an essential gene in Ewing sarcoma

CRISPR-Cas9

尤文肉瘤

Additional file 4.

NIAID Data Ecosystem40

Overexpression of HOX genes is prevalent in Ewing sarcoma and is associated with altered epigenetic regulation of developmental transcription programs

尤文肉瘤

表观遗传调控

The polycomb proteins BMI-1 and EZH2 are highly overexpressed by Ewing sarcoma (ES), a tumor of stem cell origin that is driven by EWS-ETS fusion oncogenes, most commonly EWS-FLI1. In the current stud

DataCite Commons2020-09-04 更新60

Transcriptomic analysis of depleted uranium effects on adult zebrafish and progeny. Danio rerio

环境毒理转录组

斑马鱼发育毒性

This dataset describe the transcriptomic profiling of adult brain, gonades (testis and ovaries) of adult zebrafish exposed to 20µg/L of depleted uranium for 10 days. The progeny of the exposed fishes

NIAID Data Ecosystem50

The human Ewing's Sarcoma oncoprotein EWS-FLI1 causes developmental defects in zebrafish embryos

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