Decoding NY-ESO-1 TCR T Cells: Transcriptomic Insights Reveal Dual Mechanisms of Tumor Targeting in a Melanoma Murine Xenograft Model

Single-cell RNA-seq data of NY-ESO-1-specific TCR T-cells generated with the BD Rhapsody™ system. Biogroup information: Control (n = 4), PB (murine peripheral blood, n = 4). Cell preparation: NY-ESO-1-specific TCR T-cells were obtained via a retroviral transduction of an anti-NY-ESO-1-TCR construct, murine peripheral blood T-cells were enriched using anti-CD3 magnetic separation via MojoSortTM Human CD3 Selection Kit. Single-cell analysis system: BD Rhapsody™ Library strategy: 3' mRNA sequencing Library preparation protocol: BD Rhapsody™ Targeted mRNA and Sample Tag Library Preparation mRNA panel: BD Rhapsody™ Immune Response Panel HS BD Pipeline version: 1.11L