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Identification of a novel long-range enhancer driving Sonic Hedgehog expression in neural progenitor cells. Mus musculus

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NIAID Data Ecosystem2026-03-09 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA328173
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资源简介:
A novel long-range enhancer for Shh - Shh-Brain-Enhancer-6 (SBE6) – that is located 100kb upstream of Shh and that is required for the proper induction of Shh expression during neural differentiation ChIP-on-chip for H3K4me1 and H3K27ac in ESCs and NPCs showed a gain of these two enhancer marks in NPCs at SBE6 which identified this sequence as having potential enhancer activity. Overall design: Comparison of H3K4me1 and H3K27ac profiles between ESCs and NPCs at the Shh locus
创建时间:
2016-07-07
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