Crystal structure of HIV-1 reverse transcriptase in complex with N1-heterocycle pyrimidinedione non-nucleoside inhibitor

Crystal structure of HIV-1 reverse transcriptase in complex with N1-heterocycle pyrimidinedione non-nucleoside inhibitor Descriptor: 3-({3-[(2-amino-6-fluoropyridin-4-yl)methyl]-5-(1-methylethyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl}carbonyl)-5-methylbenzonitrile, CHLORIDE ION, HIV Reverse transcriptase, ... Authors: Lansdon, E.B, Mitchell, M.L. Deposit date: 2010-01-06 Release date: 2010-02-23 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: N1-Heterocyclic pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase. Bioorg.Med.Chem.Lett., 20, 2010

本数据集收录HIV-1逆转录酶（HIV-1 reverse transcriptase）与N1-杂环嘧啶二酮类非核苷抑制剂的复合物晶体结构，复合物组分包括：3-({3-[(2-氨基-6-氟吡啶-4-基)甲基]-5-(1-甲基乙基)-2,6-二氧代-1,2,3,6-四氢嘧啶-4-基}羰基)-5-甲基苯甲腈、氯离子（CHLORIDE ION）以及HIV逆转录酶。作者：Lansdon, E.B.、Mitchell, M.L.。数据存储日期：2010-01-06，发布日期：2010-02-23，最后修改日期：2023-09-06。实验表征方法：X射线衍射（X-RAY DIFFRACTION），分辨率为2.3埃（2.3 Å）。引用文献：《N1-Heterocyclic pyrimidinediones as non-nucleoside inhibitors of HIV-1 reverse transcriptase》，发表于《Bioorg.Med.Chem.Lett.》20卷，2010年。