Details of patients carrying mutations in two or more genes.

Mutation nomenclature follows the recommended guidelines of the Human Genome Variation Society with the nucleotide numbering based on GenBank reference sequence indicated by its accession NCBI number. Details were listed in S2 Table. Abbreviations and definitions are as follows: FH, family history; HBOCS, hereditary breast and ovarian cancer syndrome; Br, breast; FA, Fanconi anemia; Lym, lymphoma; LS, Lynch syndrome; FAP2, familial adenomatous polyposis, 2; WS, werner syndrome; and CVID2, common variable immune deficiency,2.
Details of patients carrying mutations in two or more genes.