DNA glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with an enzyme-generated abasic site product (AP) and crystalized with calcium acetate

DNA glycosylase MutY variant N146S in complex with DNA containing d(8-oxo-G) paired with an enzyme-generated abasic site product (AP) and crystalized with calcium acetate Descriptor: ACETATE ION, Adenine DNA glycosylase, CALCIUM ION, ... Authors: Demir, M, Russelburg, L.P, Horvath, M.P, David, S.S. Deposit date: 2022-07-30 Release date: 2022-11-30 Last modified: 2026-08-12 Method: X-RAY DIFFRACTION (2.36 Å) Cite: Structural snapshots of base excision by the cancer-associated variant MutY N146S reveal a retaining mechanism. Nucleic Acids Res., 51, 2023本数据集为DNA糖苷酶MutY变异体N146S与携带d(8-氧代鸟嘌呤（d(8-oxo-G)）且该碱基与酶促生成的无碱基位点产物（AP位点）配对的DNA形成的复合物，经乙酸钙结晶制得。 描述符：乙酸根离子、腺嘌呤DNA糖苷酶、钙离子…… 作者：Demir, M.、Russelburg, L.P.、Horvath, M.P.、David, S.S. 存档日期：2022-07-30 发布日期：2022-11-30 最后更新日期：2023-10-25 实验方法：X射线衍射（分辨率2.36 Å） 引用文献：《癌症相关MutY N146S变异体的碱基切除结构快照揭示保留型机制》，《核酸研究》（Nucleic Acids Res.），51卷，2023年