Chromosomal location has a significant effect on the evolutionary dynamics of genes involved in sexual dimorphism, impacting both the pattern of sex-specific gene expression and the rate of duplicatio

NIAID Data Ecosystem50

High-resolution comparative genome hybridization survey of healthy individuals (chromosome 22). Homo sapiens

比较基因组杂交技术

拷贝数变异

HighRes-CGH arrays that utilize ˜385,000 distinct oligonucleotide probes to cover chromosome 22 at 85 bp resolution (tiling path step size) were designed and synthesized as previously described (Urban

NIAID Data Ecosystem30

Experimental analysis of oligonucleotide microarray design criteria to detect deletions by CGH. Experimental analysis of oligonucleotide microarray design criteria to detect deletions by CGH

比较基因组杂交技术

基因缺失检测

BACKGROUND: Microarray comparative genomic hybridization (CGH) is currently one of the most powerful techniques to measure DNA copy number in large genomes. In humans, microarray CGH is widely used to

NIAID Data Ecosystem50

High Resolution Mapping of DNA Copy Alterations in Human Chromosome 22 Using High Density Tiling Oligonucleotide Arrays

DNA拷贝数变异

比较基因组杂交技术

Deletions and amplifications of the human genomic sequence (Copy Number Polymorphisms, or 'CNPs') are the cause for numerous diseases and a potential cause of phenotypic variation in the normal popula

NIAID Data Ecosystem50

Regeneration of comparative genomic hybridization oligonucleotide microarrays with dimethylurea

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