Additional file 2 of Gene expression variability in long-term survivors of childhood cancer and cancer-free controls in response to ionizing irradiation

Additional file 2. Results of the gene expression variability classification. a Gene classifications in whole data set (WDS) and classifications after cross-validation (cv) in fibroblasts of cancer-free controls (N0), childhood cancer survivors without (N1) and with at least one second primary neoplasm (N2 +) after exposure 0 Gray. 1 = Hypo-Variable, 2 = Non-Variable, 3 = Hyper-Variable. NA = Gene excluded by bimodal test/NA in CV = classification from WDS not verified, set to 2 for further analyses. b Gene classifications in whole data set (WDS) and classifications after cross-validation (cv) in fibroblasts of cancer-free controls (N0), long-term survivors of childhood cancer without (N1) and with at least one second primary neoplasm (N2 +) after exposure to 0.05 Gray. 1 = Hypo-Variable, 2 = Non-Variable, 3 = Hyper-Variable. NA = Gene excluded by bimodal test/NA in CV = classification from WDS not verified, set to 2 for further analyses. c Gene classifications in whole data set (WDS) and classifications after cross-validation (cv) in fibroblasts of cancer-free controls (N0), long-term survivors of childhood cancer without (N1) and with at least one second primary neoplasm (N2 +) after exposure to 2 Gray. 1 = Hypo-Variable, 2 = Non-Variable, 3 = Hyper-Variable. NA = Gene excluded by bimodal test/NA in CV = classification from WDS not verified, set to 2 for further analyses. d Results of the various employed algorithms for the classification of N1 and N2 + using 30 genes that were only classified as hyper-variable in N2 + post-LDIR. Models were trained and tested using only N1 and N2 + data post-LDIR.