Crystal structure of a recombinant glutathione transferase, created by replacing the last seven residues of each subunit of the human class pi isoenzyme with the additional C-terminal helix of human class alpha isoenzyme

Crystal structure of a recombinant glutathione transferase, created by replacing the last seven residues of each subunit of the human class pi isoenzyme with the additional C-terminal helix of human class alpha isoenzyme Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLUTATHIONE, Glutathione S-transferase class pi chimaera (CODA), ... Authors: Kong, G.K.W, Micaloni, C, Mazzetti, A.P, Nuccetelli, M, Antonini, G, Stella, L, McKinstry, W.J, Polekhina, G, Rossjohn, J, Federici, G, Ricci, G, Parker, M.W, Lo Bello, M. Deposit date: 2002-04-04 Release date: 2002-04-17 Last modified: 2023-08-16 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Engineering a new C-terminal tail in the H-site of human glutathione transferase P1-1: structural and functional consequences. J.Mol.Biol., 325, 2003

本数据集为一株重组谷胱甘肽转移酶（glutathione transferase）的晶体结构，该重组酶通过将人类π类同工酶每个亚基的最后7个残基替换为人类α类同工酶的额外C端螺旋构建得到。数据集标注：2-(N-吗啉代)乙磺酸（2-(N-MORPHOLINO)-ETHANESULFONIC ACID）、谷胱甘肽、谷胱甘肽S-转移酶（Glutathione S-transferase）π类嵌合体（CODA）…… 作者：Kong, G.K.W、Micaloni, C、Mazzetti, A.P、Nuccetelli, M、Antonini, G、Stella, L、McKinstry, W.J、Polekhina, G、Rossjohn, J、Federici, G、Ricci, G、Parker, M.W、Lo Bello, M。存放日期：2002年4月4日；发布日期：2002年4月17日；最后修改日期：2023年8月16日。实验方法：X射线衍射（X-RAY DIFFRACTION），分辨率1.86埃（Å）。引用文献：《人类谷胱甘肽转移酶P1-1的H位点构建新型C端尾：结构与功能效应》，《分子生物学杂志》，2003年，第325卷。