Transcriptomic profiles of Candida albicans grown in the presence or absence of mucin glycans. Transcriptomic profiles of Candida albicans grown in the presence or absence of mucin glycans

We use high-throughput sequencing to profile the response of the opportunistic fungal pathogen Candida albicans to mucins and mucin-glycans from the mucosal niche. We find that C. albicans undergoes a genome-wide phenotypic shift in response to mucins and their attached glycans suppressing virulence-associated pathways. Overall design: Examination of differential gene expression in C. albicans in response to mucin sugars