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Compartment TFV and TFVdp efficacy concentrations (EC50,90,95) predicted by logistic regression to suppress HIV infection following single oral TDF, single topical TFV 1% gel and 7-day topical TFV 1% gel in vivo product use.

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Figshare2015-12-02 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_Compartment_TFV_and_TFVdp_efficacy_concentrations_EC_50_90_95_predicted_by_logistic_regression_to_suppress_HIV_infection_following_single_oral_TDF_single_topical_TFV_1_gel_and_7_day_topical_TFV_1_gel_in_vivo_product_use_/1220852
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§Predicted compartment dose concentrations to suppress 50, 90 and 95% of HIV infection interpolated from the logistic regression probability curve where infection was defined as cumulative p24 pg/mL ≥500.Actual drug concentrations in the delivered product were 300 mg tenofovir disoproxil fumarate in the oral pill (equivalent to 245 mg of tenofovir disoproxil) and 40 mg/4 mL tenofovir in each topical gel application.Compartment TFV and TFVdp efficacy concentrations (EC50,90,95) predicted by logistic regression to suppress HIV infection following single oral TDF, single topical TFV 1% gel and 7-day topical TFV 1% gel in vivo product use.
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2015-12-02
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