TMT-based proteome and phosphoproteome profiling of control and GPR146 knockdown SGBS cells

This dataset contains quantitative proteome and phosphoproteome profiles of control and GPR146 knockdown SGBS human preadipocyte cells. Cells were processed for tandem mass tag (TMT)–based multiplexed quantitative mass spectrometry, with parallel analysis of total proteome input samples and TiO2-enriched phosphopeptides. The study aims to characterize global protein abundance and phosphorylation changes associated with GPR146 depletion. The dataset includes raw mass spectrometry files, processed identification and quantification results, and the protein sequence database used for analysis.