FOXP3-mediated inhibition of a global gene regulator is required for maintaining Treg cell commitment
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE16990
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资源简介：
Regulatory T (Treg) cells are characterized by the forkhead transcription factor FOXP3. Mutations in FOXP3 cause autoimmunity in mice and humans. Here, Treg cells as well as conventional T cells were isolated from B-CLL patients and analyzed by global gene expression analysis in order to identify biological differences in Treg cells of CLL patients. Freshly isolated peripheral CD4+ T cells of CLL patients, separated into CD25 negative and positive subpopulations.
创建时间：
2017-05-31
