Additional file 3: of The atypical RhoGTPase RhoE/Rnd3 is a key molecule to acquire a neuroprotective phenotype in microglia

Table S2. List of siRNA targets resulting in negative differential circularity. Primary microglia were transfected with a pool of siRNA oligonucleotides against each gene and tested for their effect on CM-induced microglia ramification, which was expressed as differential circularity. siRNAs that resulted in negative differential circularity values were selected and sorted by their fold discovery rate (FDR). Statistically significant genes were marked in bold. Genes that were annotated by the Parkinson’s UK Gene Ontology Project [22] are marked in the PD genes column. Genes that were listed in the PD map tool of the University of Luxembourg ( http://pdmap.uni.lu/minerva/ ) are marked in the PD map column [23]. Genes overlapping with differential transcriptome expression data from post mortem tissue of the substantia nigra [24] published on the PD map webpage ( http://pdmap.uni.lu/minerva/ ) are marked in the last column. (XLSX 56 kb)