Structure of PDE6C in complex with inhibitory cone p gamma in the presence of cGMP

Structure of PDE6C in complex with inhibitory cone p gamma in the presence of cGMP Descriptor: CYCLIC GUANOSINE MONOPHOSPHATE, Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha', GUANOSINE-5'-MONOPHOSPHATE, ... Authors: Srivastava, D, Singh, S, Artemyev, N. Deposit date: 2024-07-31 Release date: 2024-12-18 Last modified: 2025-05-21 Method: ELECTRON MICROSCOPY (3 Å) Cite: Structural and functional dynamics of human cone cGMP-phosphodiesterase important for photopic vision. Proc.Natl.Acad.Sci.USA, 122, 2025

存在环磷酸鸟苷（cyclic guanosine monophosphate, cGMP）时，抑制性视锥蛋白γ亚基与磷酸二酯酶6C（PDE6C）复合物的结构。描述项：环磷酸鸟苷（cGMP）、视锥细胞特异性3',5'-环磷酸鸟苷磷酸二酯酶α'亚基、鸟苷-5'-一磷酸…… 作者：Srivastava D、Singh S、Artemyev N。提交日期：2024-07-31；发布日期：2024-12-18；最后修改日期：2025-05-21。实验方法：电子显微镜（分辨率3 Å）。引用文献：《人视锥细胞cGMP磷酸二酯酶的结构与功能动态特性：明视觉功能的关键调控因子》，《美国国家科学院院刊》，122卷，2025年。