Expression analysis in Patl2-knock-out mouse oocytes (GV and MII stages). Mus musculus

The oocyte maturation is a poorly understood process. Patl2 is involved in human bad egg syndrome and is a translation factor. The aim of this study was to assess the impact of the lack of Patl2 on the transcriptomes of GV and MII oocytes. Overall design: Mouse oocytes from wild type and Patl2-knock-out mouse were collected at GV and MII stages. Total RNA were purified and analyzed on mouse ClariomD Affymetrix arrays. The experiment included five GV stage oocyte samples (two wild type and three Patl2-KO) and five GMII stage oocytes samples (two wild-type and three Patl2-KO).