Regression analyses of ITS on the changes in antibiotic consumption.

Changes in level and slope in antibiotic prescribing rates in inpatient (RATE_I), outpatient (RATE_O) and emergency (RATE_E) settings in the 65 general hospitals were analyzed using segmented regression analysis of ITS. The intensity of antibiotic consumption was expressed as DDD/100 bed-days for inpatient settings (DDD_I) or DDD/1000 outpatient-days for outpatient settings (DDD_O). The parameters of β1 to β5, expressed as Mean (SE), were described in the Methods. *p < 0.05; **p < 0.01; ***p < 0.001. Regression analyses of ITS on the changes in antibiotic consumption.