RNA-seq of bone marrow derived macrophages stimulated with monophosphoryl lipid A (MPLA)
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE111730
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We found that MPLA reprograms macrophages in a way that supports a persistent monocyte/macrophage chemokine secretion profile reflected in macrophage mRNA. Additionally, this RNA-seq data revealed that certain genes (e.g. phagocytosis-related) persist much longer after MPLA than others (e.g. pro-inflammatory cytokines). Bone marrow derived macrophages were harvested for RNA after 4hrs of monophosphoryl lipid A (MPLA) priming, 24hrs of MPLA priming, and 3 days following the end of priming
创建时间：
2019-02-11
