Focused miRNA panel – miRNAs significantly associated with time to disease progression.

a Interaction tests were performed for all patients and for patients with distal (sigmoid and rectum) and proximal (cecum to descending) primary tumor location, separately.b Hazard ratio is per inter-quartile range expression increase and is adjusted for age, sex, number of metastatic sites, prior adjuvant treatment and primary tumor location.c miRNA was missing in >10% of samples so interaction was not tested.Abbreviations: HR, hazard ratio; CI, confidence interval.Focused miRNA panel – miRNAs significantly associated with time to disease progression.