Cut&Run on Id4-GFP bright + med germ cells (~SSC) at 10dpp for H3K27me3, H3K27ac and H3K9me3

To evaluate the impacts of Dnmt3A mutation in the methylome of male germ cells, mutant and control whole genome bisulfite sequencing experiments were conducted starting from genomic DNA obtained from FACS-sorted germ cells. Examination of 3 different histone modifications in Dnmt3A mutant and wildtype context.