Additional file 1 of Identification of novel protein biomarkers and drug targets for colorectal cancer by integrating human plasma proteome with genome

Additional file 1: Table S1. Summary of colorectal cancer (CRC), colon cancer, and rectal cancer datasets used in the current study. Table S2. Summary of proteins datasets used in the current study. Table S3. Genetic instruments for plasma proteins. Table S4. Results of 13 proteome-wide Mendelian randomization identified proteins for colorectal cancer risk. Table S5. All results of discovery proteome-wide Mendelian randomization for colorectal cancer risk. Table S6. Mendelian randomization results of 13 proteins with colon cancer risk. Table S7. Mendelian randomization results of 13 proteins with rectal cancer risk. Table S8. All results of proteome-wide Mendelian randomization for colorectal cancer risk using only cis pQTLs. Table S9: Colocalization results across different priors and windows. Table S10: Druggability of proteins potentially causally associated with colorectal cancer.