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Data from: A classification system for zebrafish adipose tissues

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DataONE2017-03-16 更新2024-06-26 收录
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Zebrafish are increasingly being used to study adipose tissue (AT) biology, and offer significant utility for in vivo imaging of adiposity dynamics and large-scale screens to identify adiposity modifiers. In particular, AT can be accurately quantified in live zebrafish using fluorescent lipophilic dyes (FLDs). Although, this methodology offers considerable promise, the comprehensive identification and classification of zebrafish ATs has not been performed. Here we utilize FLDs and in vivo imaging to systematically identify, classify and quantify the zebrafish AT pool. We identify 34 regionally distinct zebrafish ATs, including 5 visceral ATs (VATs) and 22 subcutaneous ATs (SATs). For each of these ATs we describe detailed morphological characteristics to aid their identification in future studies. Further, we quantify the areas for each AT, and construct regression models to enable the prediction of expected AT size and variation across a range of developmental stages. Together, this resource provides foundational information on the identity, dynamics, and expected quantities of zebrafish ATs for use as a reference for future studies.
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2017-03-16
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