Effects of androgen receptor degradation by PROTAC ARCC-32 on gene expression in LN95 prostate cancer cells
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https://www.ncbi.nlm.nih.gov/sra/SRP312568
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资源简介：
RNA-seq was performed in duplicate on LN95 prostate cancer cells at 16, 24, and 48 hours after degrdation of full length androgen recpetor by ARCC-32 Overall design: LN95 prostate cancer cells, which express both full length androgen receptor (AR-FL) and the V7 splice variant (AR-V7) were cultured in steroid depelted medium. They were then treated with a PROTAC (ARCC-32) that selectively degrades AR-FL, and assessed for gene expression in duplicate after 16, 24, or 48 hours versus vehicle control treated cells.
创建时间：
2021-03-31
